Charge XL — Detailed Product Information

Charge XL is a combination product containing:

• Tadalafil 20 mg — used to help improve erectile function by increasing blood flow to the penis during sexual stimulation.
• Dapoxetine 60 mg — used for the treatment of premature ejaculation (PE) by helping improve control over ejaculation and potentially increasing the time to ejaculation.

How it may help

Charge XL may be considered for adult men who experience both erectile dysfunction and premature ejaculation, subject to assessment by a qualified healthcare professional. It does not increase sexual desire on its own, and tadalafil requires sexual stimulation to help produce an erection.

How to use Charge XL

Because this product contains the relatively high dapoxetine 60 mg strength, do not self-adjust the dose. Dapoxetine treatment is generally started at 30 mg and increased to 60 mg only when appropriate and tolerated, it should not be taken more frequently than once every 24 hours. Tadalafil 20 mg is also an on-demand strength and should not be taken more than once daily. Therefore, use Charge XL exactly as prescribed or directed by a qualified healthcare professional.

General use guidance:

• Swallow the tablet whole with water.
• It may generally be taken with or without food.
• Do not take an extra dose if the desired effect is not achieved.
• Do not combine it with other erectile dysfunction medicines or dapoxetine-containing products unless specifically instructed by a clinician.
• Follow the timing prescribed by your healthcare professional; dapoxetine alone is generally used 1–3 hours before anticipated sexual activity.

DOs

• Do consult a doctor or pharmacist before use, especially if you have heart, liver, kidney, blood pressure, or mental health conditions.
• Do disclose all medicines and supplements you are taking.
• Do stay well hydrated, particularly because dapoxetine can cause dizziness or fainting in some people.
• Do stop sexual activity and seek medical help if you experience chest pain or severe symptoms.
• Do seek urgent medical attention for an erection lasting more than 4 hours or for sudden vision or hearing problems.

DONTs

Do NOT use Charge XL with nitrate medicines, such as nitroglycerin or isosorbide, because combining nitrates with tadalafil can cause a dangerous drop in blood pressure. Tadalafil is also contraindicated with riociguat, a guanylate cyclase stimulator.

Also:

• Do not exceed the prescribed dose or use it more frequently than directed.
• Do not combine it with other PDE5 inhibitors such as sildenafil or vardenafil without medical advice.
• Avoid or limit alcohol, particularly because it may worsen dizziness, fainting, and blood-pressure effects.
• Do not drive or operate machinery if you feel dizzy, faint, or unusually drowsy.
• Do not use dapoxetine-containing treatment together with certain antidepressants or other interacting medicines without professional advice.
• Do not use it if sexual activity has been advised against because of an unstable or serious cardiovascular condition.

Possible side effects

Some users may experience:

• Headache
• Dizziness or light-headedness
• Nausea
• Flushing
• Indigestion
• Nasal congestion
• Diarrhea or dry mouth
• Difficulty sleeping
• Back or muscle pain

Dapoxetine may cause dizziness, fainting, or a sudden drop in blood pressure, while tadalafil can also interact with medicines that affect blood pressure. The 60 mg dapoxetine dose is associated with a higher frequency and severity of adverse effects than lower doses.

Important safety message

Charge XL is intended for adult men and should be used under the guidance of a qualified healthcare professional. Erectile difficulties and premature ejaculation can sometimes be associated with cardiovascular disease, diabetes, psychological factors, hormonal issues, or medication effects, so persistent symptoms should be medically assessed.

Suggested product disclaimer:
Prescription/healthcare professional guidance recommended. Not suitable for everyone. Do not use with nitrates. Read the product information and consult a qualified healthcare professional before use